My co-authors and I published a peer reviewed journal paper developing a method to measure arterial tortuosity and validated the method by measuring an increase in tortuosity in a hypertensive population. The idea is that vascular disease may twist the arteries and we developed a method to measure this twisting.
Other significant findings included the use of interpolating lower resolution images to higher resolution in order to compare images taking at different resolution. This is important because it allows comparison of existing images. Researchers won't have to reimage patients all at the same resolution reducing the cost of conducting research and clinically patients can be tracked over time even if different medical imaging equipment and resolutions are used. The full article is here: http://www.biomedcentral.com/1471-2105/12/S10/S15